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PrEP and Related Checkups

PrEP and Related Checkups
PEP治療計劃

PrEP前檢查

PrEP (pre-exposure prophylaxis) is a method that people at risk for HIV take to prevent getting HIV from sex or injection drug use. When taken as prescribed, PrEP is highly effective for preventing HIV infection. However, PrEP does not prevent other infections like HPV, Syphilis, Chlamydia or Herpes.

In 2020, 130 countries including South Korea, New Zealand, Australia, UK, USA, Vietnam, Thailand, etc., reported that they had adopted the WHO recommendations on oral PrEP in national guidelines, with a further 23 countries reporting that they plan to adopt the recommendations in the next two years.

PrEP in Hong Kong can be obtained from private clinics or hospitals. If you are interested in getting PrEP in Hong Kong, make sure you have read the instructions and done the corresponding tests needed.

MY PrEP HK Service Introduction Video:
MY PrEP HK Introduction

What is PrEP?

Pre-exposure prophylaxis (PrEP) is the use of anti-HIV medication under a doctor's advice to prevent HIV infection.

It is suitable for people who are HIV-negative but at risk of getting the virus. Truvada (emtricitabine-tenofovir DF) is a patented drug used for PrEP.

Please note that PrEP is not a vaccine. It can effectively prevent HIV infection from sex or injecting drugs only when taken correctly under a doctor's advice. If PrEP is used inconsistently, it will not work.

If you are thinking about using PrEP, you can make a reservation for the MY PrEP service to get the proper check-ups, doctor consultation and prescription.

Is there any side effect of PrEP?

The pill used for PrEP, Truvada®(also called FTC/TDF), has been used to treat people with HIV since 2004.

The U.S. Food and Drug Administration (FDA) approved Truvada for PrEP use in 2012.

Adverse effects reported with PrEP are generally nonspecific and mild. However, renal function test was noted to be elevated and bone mineral density (BMD) decreased. In HIV infected patients, TDF/FTC is associated with liver and kidney complications. The possibility therefore exists that clinically significant toxicity may occur after prolonged use, particularly in those who have preexisting impaired renal function or osteoporosis.

That is why, it is very important to get the proper checkups and make sure you are HIV negative before using PrEP. Consult a doctor to know more about the PrEP checkups and medication.

Crucial steps before getting PrEP

You need to have the right medical check-up to be sure it is safe for you to use PrEP and you need to buy from a reliable supplier.

Get PrEP in THREE steps:

  • You must take an HIV test and be sure that you are HIV-negative to avoid developing drug resistance to anti-HIV medication.
  • You also need to be tested to ensure that you have good kidney and liver function.
  • Consult a doctor and understand your dosage for PrEP – daily or on-demand.

If you are thinking about using PrEP, you can make a reservation for the My PrEP service to get the proper check-ups, doctor consultation and prescription.

How do I take PrEP?

If you are using PrEP correctly, it is very unlikely that you will get HIV. Research studies show that PrEP reduces the risk level of someone with HIV infecting you by more than 99%. There are 2 ways of taking PrEP, you just need to select either way.

Consult your doctor before deciding which method is suitable for you. Remember, it is important to follow the directions strictly to make PrEP useful in HIV prevention.

Daily PrEP

PrEP is most commonly taken as a once-a-day-pill. The easiest method for all genders is to take PrEP daily – take one pill at the same time each day.

If you are biologically male and not taking exogenous estradiol-based hormones, you are suggested to start the regimen by taking 2 PrEP pills 2-24 hours before having sex.

If you are biologically female or gender diverse people, start with taking 1 PrEP pill daily for 7 days before potential sexual exposure.


On demand PrEP

Some people are taking PrEP before and after sex (on demand).This method only works for biologically male who are not taking exogenous estradiol-based hormones.And this works only when the sexual activity is planned.

Take 2 pills 2-24 hours before sex, then 1 pill 24 hours after the first dose and another pill 48 hours after first dose. This is called 2-1-1 dosing.

In the event of sex on several days in a row, 1 pill should be taken each day until 48 hours after the last sexual intercourse.

If you are thinking about using PrEP, you can make a reservation for the My PrEP service to get the proper check-ups, doctor consultation and prescription.

How to Buy PrEP Medication in Hong Kong

PrEP is not available from the public hospitals in Hong Kong. If you would like to get PrEP in Hong Kong, you may visit private clinics or hospitals to do the checkups needed and get the prescription from a doctor.

You may download the leaflet below to know more about steps of getting PrEP in Hong Kong.


What To Do

You need to have the right medical check-up to be sure it is safe for you to use PrEP and you need to buy from a reliable supplier.


我該怎樣做?

在購買PrEP藥物前,你必須先進行適當的體檢,以確保使用PrEP藥物的安全性,你亦需要從可靠的供應商處購買PrEP藥物。

首先進行適當的體檢及獲得PrEP藥物的醫生處方。

你可以選擇使用 MY PLACE 的 MY PrEP服務 來進行所需的體檢及約見醫生。如果你的身體狀況適合使用PrEP藥物,醫生會為你提供處方。

下一步你需要帶同處方購買藥物,你可透過以下任何一種方式在香港購買PrEP藥物:

  1. 於 MY PLACE 購買「舒發泰Truvada」價錢:$6,500/瓶 (30粒裝),或於MY PLACE購買加拿大製副廠藥「APO-EMTRICITABINE-TENOFOVIR」價錢:$1,200(30粒裝)
  2. 帶著處方到位於中環的創健醫療 購買Teno-Em 價錢:$1,200/瓶 (30粒裝) 你需要即場登記成為顧客方可購買。
  3. 在其他私營機構購買「舒發泰Truvada」或副廠藥物。

PrEP身體檢查及藥物價錢

MY PLACE (非牟利機構的社企)

首次體檢及醫生諮詢: $1,550
服藥後定期體檢及醫生諮詢:$1,350-$1,550
藥物「舒發泰Truvada」: $6,500/瓶 (30粒裝) 或
藥物「APO-EMTRICITABINE-TENOFOVIR」:$1,200/瓶 (30粒裝)
你亦可帶同處方到創健醫療購買Teno-Em:$1,200/瓶 (30粒裝)


中環創健醫療

首次體檢及醫生諮詢:$3,500-$4,200
服藥後定期體檢及醫生諮詢:$1,500-$1,800
藥物「舒發泰Truvada」: $8,550/瓶 (30粒裝)
Teno-Em :$1,200/瓶 (30粒裝)


香港其他診所

價錢不一,需自行查詢。

*注意:如果你已經得到MY PLACE 的醫生處方,則無須再次進行體檢便可購買PrEP藥物。
到達診所時,你只需要出示醫生處方及體檢證明便可購買PrEP藥物。

MY PrEP服務時段及收費

「關懷愛滋」旗下的MY PLACE是一所非牟利的性健康服務中心,我們服務包括LGBT+在內的所有性/別人士。當中的MY PrEP服務提供香港PrEP藥物購買、身體檢查及醫生處方服務,有關香港PrEP價錢及檢查收費詳情如下:

PEP治療計劃

香港緊急暴露後預防性投藥(PEP)療程

暴露後預防性投藥,又稱為PEP 療程(Post-Exposure Prophylaxis),療程的目的是減低高危性行為、共用注射針頭後感染愛滋病病毒(HIV)的風險,只要於高危性行為後72小時之內根據醫生指示開始服用暴露後預防性投藥(PEP),經過28日定時定量服藥,能夠成功阻斷81%以上的愛滋病病毒(HIV)感染機會,越早開始暴露後預防性投藥(PEP)療程,阻斷機會越大。 MY PLACE提供緊急暴露後預防性投藥(PEP)療程供有需要人士使用,如有需要,可參考以下資訊。

由於PEP療程屬於緊急情況使用,如您有需要,請直接WhatsApp 52268394查詢,毋須經電腦系統預約,以免錯失治療時機。

緊急暴露後預防性投藥(PEP)療程

療程的價格按所使用之藥物有以下選擇:

  1. Truvada + Isentress:$13,500
  2. Biktarvy:$12,860

不論選擇那一種藥物,整個療程都會包括:
3 次醫生診斷及跟進(第1天、第7天及第49天)、7 項測試28 天PEP藥物。

*如個案屬於緊急而於非辦公時段到診,有可能需要額外收取$1,000作為緊急應診之費用。


MY PLACE的緊急暴露後預防性投藥(PEP)療程包括:

  • 服藥前的首次醫生評估及諮詢
  • 服藥前的愛滋病病毒(HIV)快速測試
  • 28日阻斷愛滋病病毒(HIV)的PEP正廠藥物
  • 兩次覆診醫生諮詢及解讀報告
  • 愛滋病病毒(HIV)P24抗原和抗體測試
  • 肝腎功能檢查
  • 梅毒檢測
  • 乙型肝炎檢測
  • 丙型肝炎檢測

我適合使用暴露後預防性投藥(PEP)嗎?

一般而言,決定一個人適合服用暴露後預防性投藥(PEP),需要符合以下兩個條件:

  1. 距離疑似接觸愛滋病病毒(HIV)時間不超過72小時;
  2. 接觸者在此之前並未感染愛滋病病毒(HIV)

如您符合以上兩個條件,而又想及早進阻斷愛滋病病毒(HIV)入侵的話,您便可以選擇MY PLACE的「緊急暴露後預防性投藥(PEP)療程」。

暴露後預防性投藥(PEP)的原理是甚麼?

選擇一:Truvada + Isentress

本處方會採用兩種預防藥物Truvada及Isentress,兩者皆為正廠藥物,共同使用可阻斷愛滋病病毒(HIV)入侵白血球細胞。Truvada是一種用以治療及預防愛滋病病毒(HIV)感染的藥物,能抑制愛滋病病毒(HIV)在人體內複製;而Isentress屬於嵌入酶的抑制劑,能夠抑制愛滋病病毒(HIV)內嵌入酶的催化活性,並且可以阻斷愛滋病病毒(HIV)的雙股DNA共價插入或嵌入宿主細胞DNA的作用。根據醫生指示合併使用此兩種不同功能的藥物,可有效阻斷愛滋病病毒(HIV)的入侵。此處方乃根據衛生防護中心愛滋病病毒非職業暴露後預防藥物的使用建議 (二零一八年十一月) 版本所定。[1]


選擇二:Biktarvy

本處方為單錠復方藥物,結合Tenofovir alafenamide (50mg) , emtricitabine (200mg) 及bictegravir (25mg)(TAF/FTC/BIC)三種藥物效能來抑制反轉錄酶及嵌合酶的作用。由於Biktarvy屬於較新型藥物,現時並未包括在香港衛生防護中心愛滋病病毒非職業暴露後預防藥物的使用建議 (二零一八年十一月) 內。但自2020年起Biktarvy於美國、歐洲及台灣的愛滋病治療指引當中已經陸續列入可採用之PEP藥物列表之內[2]。現時,醫生會按臨床診斷決定處方Biktarvy作為藥品仿單標示外使用 (Off-Label Use)


備註:

  1. Recommendations on the use of non-occupational post-exposure prophylaxis against HIV (Nov, 2018);
    https://www.chp.gov.hk/files/pdf/recommendations_on_the_use_of_non_occupational_post_exposure_prophylaxis_against_hiv_november2018.pdf
  2. European AIDS Clinical Society Guidelines. October 2021.
    https://www.eacsociety.org/media/final2021eacsguidelinesv11.0_oct2021.pdf

暴露後預防性投藥(PEP)有副作用嗎?

服用暴露後預防性投藥(PEP)藥物必須經醫生充分評估及處方,由於暴露後預防性投藥(PEP)療程的藥物屬於高劑量抗逆轉錄病毒的藥物,其副作用可以很強,亦因人而異,一般包括腹瀉、頭痛、噁心及嘔吐,但這些副作用會在停止用藥後消失。


由於暴露後預防性投藥(PEP)藥物需要良好的肝臟及腎臟機能排走代謝物,對於肝腎功能不足者必須加以監察,如出現不適情況時,有可能需要停止療程。

暴露後預防性投藥(PEP)療程期間的支援服務

MY PLACE的緊急暴露後預防性投藥(PEP)療程附設諮詢及跟進服務,如果在開展療程後仍然感到擔憂或焦慮不安,你可於療程期間尋求「關懷愛滋」轄下的男士健康團隊「有種部隊」支援 (WhatsApp號碼: 6387 5551)。